Single-strand DNA breaks cause replisome disassembly

Vrtis K., Dewar J., Chistol G., Wu A.R., Graham T.G.W., Walter J.C. Molecular Cell, 81:1309-18 (2021). [PDF]

The DNA replication fork suppresses CMG unloading from chromatin before termination

Low* E., Chistol* G [@]., Zaher M.S., Kochenova O.V., Walter J.C [@]. Genes & Development, 34:1534-45 (2020). [PDF]

* – these authors contributed equally.
[@] – corresponding authors

TRAIP Is a Master Regulator of DNA Interstrand Crosslink Repair

Wu R.A., Semlow D.R., Kamimae-Lanning A.N., Kochenova O.V., Chistol G. , Hodskinson M.R., Amunugama R., Sparks J.L., Wang M., Deng L., Mimoso C.A., Low E., Patel K.J., Walter J.C. Nature. 567(7747):267-72 (2019).

The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair

Sparks J.L.*, Chistol G.*, Gao A.O., Räschle M., Larsen N.B., Mann M., Duxin J.P., & Walter J.C. Cell, 176, 167-81.e21 (2019). [PDF]

Mechanochemical Coupling and Bi-Phasic Force-Velocity Dependence in the Ultra-Fast Ring ATPase SpoIIIE

Liu N.*, Chistol G.*, Cui Y. & Bustamante C. eLife, 7 (2018). [PDF]

Two-subunit DNA Escort Mechanism And Inactive Subunit Bypass In An Ultra-Fast Ring ATPase

Liu N.*, Chistol G.* & Bustamante, C. eLife, 4 (2015). [PDF]

[Review] Mechanical Operation and Intersubunit Coordination of Ring-Shaped Molecular Motors: Insights from Single-Molecule Studies

Liu S.*, Chistol G.* & Bustamante C. Biophysical Journal, 106, 1844–58 (2014). [PDF]

[Preview] Molecular Watchdogs on Genome Patrol

Chistol G. & Walter J.C. eLife 3, e02854 (2014). [PDF]

A Viral Packaging Motor Varies Its DNA Rotation and Step Size to Preserve Subunit Coordination as the Capsid Fills

Liu S.*, Chistol G.*, Hetherington C.L.*, Tafoya S., Aathavan K., Schnitzbauer J., Grimes S., Jardine P.J., & Bustamante C. Cell 157, 702–13 (2014). [PDF]

High Degree of Coordination and Division of Labor Among Subunits in a Homomeric Ring ATPase

Chistol G.*, Liu S.*, Hetherington C.L., Moffitt J.R., Grimes S., Jardine P.J., & Bustamante C. Cell 151, 1017–28 (2012). [PDF]

ClpX(P) Generates Mechanical Force to Unfold and Translocate Its Protein Substrates

Maillard R.A., Chistol G., Sen M., Righini M., Tan J., Kaiser C.M., Hodges C., Martin A., & Bustamante C. Cell 145, 459–69 (2011). [PDF]

[Preview] Single-Molecule Visualization of MCM2-7 DNA Loading: Seeing Is Believing

Chistol G. & Walter J.C. Cell 161, 429-30 (2015). [PDF]