News

Our Replication Initiation Manuscript Is Accepted at Cell :)

May 13, 2024

Our manuscript titled "Single-Molecule Imaging Reveals the Mechanism of Bidirectional Replication Initiation in Metazoa" was officially accepted for publication in Cell. The project started in the summer of 2020 (that first glorious COVID summer) when Scott started imaging how GINS is recruited to replication origins. He later did the same for Cdc45. In 2021 Riki joined the project and focused on imaging firing factors (TopBP1, RecQL4, and finally DONSON). It took a while to explore various hypotheses, sort out various technical difficulties, develop new assays, and develop new tools for analyzing the data. We submitted the paper in November 2023, and after a somewhat bumpy review process, the paper was accepted on 13th of May 2024 :)

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Tomoko Started Her Rotation

April 10, 2024

Tomoko, a 1st year CSB graduate student, just started her 2-month rotation in our lab. She will be working with Riki on understanding the mechanism of the CMG helicase activation. We're delighted to double the Japanese contingent of our lab :)

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Chistol Lab Retreat Day

August 15, 2023

Chistol Lab Retreat Day

The Chistol lab organized their annual retreat day filled with fun activities - Breakfast at the Palo Alto Creamery, mini golf, dinner at Nola's, and ending the day with a little treat at Salt & Straw Ice Creamery.

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